Introduction
Frances Kelsey was a Canadian pharmacologist who played a significant role in the development of drug regulations. She is best known for her refusal to approve thalidomide for use in the United States, which prevented thousands of birth defects in children. A book about Frances Kelsey was written to honor her achievements and contributions to the field of pharmacology.
Early Life and Education
Frances Oldham was born in British Columbia, Canada, in 1914. She was the daughter of a farmer and a schoolteacher. She graduated from high school at the age of 15 and went on to study at the University of British Columbia. She received her bachelor's degree in science in 1934 and her master's degree in science in 1936. She then went on to study at the University of Chicago, where she received her Ph.D. in pharmacology in 1938.
Early Career
Frances Kelsey began her career as a pharmacologist at the University of Chicago. She then worked for the United States Department of Agriculture, where she researched the effects of various chemicals on livestock. In 1960, she joined the United States Food and Drug Administration (FDA) as a medical officer.
Thalidomide and the FDA
In the 1950s and 1960s, thalidomide was a popular drug used to treat morning sickness in pregnant women. It was later discovered that thalidomide caused severe birth defects in children. Frances Kelsey was the FDA medical officer responsible for reviewing the drug for approval in the United States. She refused to approve the drug, citing concerns about its safety. Her refusal prevented thousands of birth defects in children.
Legacy and Honors
Frances Kelsey's work at the FDA led to significant changes in drug regulation. She was awarded the President's Award for Distinguished Federal Civilian Service by President John F. Kennedy in 1962. She was also inducted into the Canadian Medical Hall of Fame in 2008. In addition, a postage stamp featuring her image was issued in Canada in 2015.
The Book About Frances Kelsey
The book about Frances Kelsey, titled "A Pharmacologist's War: Frances Oldham Kelsey," was written by Trevor Stone. The book tells the story of Frances Kelsey's life and career, from her early years in Canada to her work at the FDA. It also explores her role in preventing the approval of thalidomide in the United States. The book is a tribute to Frances Kelsey's achievements and contributions to the field of pharmacology.
Conclusion
Frances Kelsey was a remarkable woman who made significant contributions to the field of pharmacology. Her refusal to approve thalidomide for use in the United States prevented thousands of birth defects in children. The book about Frances Kelsey is a tribute to her life and career and serves as a reminder of the importance of drug regulation and safety.